Relief of Autoinhibition Enhances Vta1 Activation of Vps4 via the Vps4 Stimulatory Element

The endosomal sorting complexes required for transport (ESCRTs) impact multiple cellular processes including multivesicular body sorting, abscission, and viral budding. The AAA-ATPase Vps4 is required for ESCRT function, and its full activity is dependent upon the co-factor Vta1. The Vta1 carboxyl-t...

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Detalhes bibliográficos
Main Authors: Norgan, Andrew P., Davies, Brian A., Azmi, Ishara F., Schroeder, Andreas S., Payne, Johanna A., Lynch, Gregory M., Xu, Zhaohui, Katzmann, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764817/
https://ncbi.nlm.nih.gov/pubmed/23880759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.494112
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