Relief of Autoinhibition Enhances Vta1 Activation of Vps4 via the Vps4 Stimulatory Element

The endosomal sorting complexes required for transport (ESCRTs) impact multiple cellular processes including multivesicular body sorting, abscission, and viral budding. The AAA-ATPase Vps4 is required for ESCRT function, and its full activity is dependent upon the co-factor Vta1. The Vta1 carboxyl-t...

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Autores principales: Norgan, Andrew P., Davies, Brian A., Azmi, Ishara F., Schroeder, Andreas S., Payne, Johanna A., Lynch, Gregory M., Xu, Zhaohui, Katzmann, David J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764817/
https://ncbi.nlm.nih.gov/pubmed/23880759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.494112
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