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Structural basis of Vta1 function in the multi-vesicular body sorting pathway

The MVB pathway plays essential roles in several eukaryotic cellular processes. Proper function of the MVB pathway requires reversible membrane association of the ESCRTs, a process catalyzed by Vps4 ATPase. Vta1 regulates the Vps4 activity but its mechanism of action was poorly understood. We report...

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Detalhes bibliográficos
Main Authors: Xiao, Junyu, Xia, Hengchuan, Zhou, Jiahai, Azmi, Ishara, Davies, Brian A., Katzmann, David J., Xu, Zhaohui
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775496/
https://ncbi.nlm.nih.gov/pubmed/18194651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2007.10.013
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