Negative Elongation Factor (NELF) Coordinates RNA Polymerase II Pausing, Premature Termination, and Chromatin Remodeling to Regulate HIV Transcription

A barrier to eradicating HIV infection is targeting and eliminating latently infected cells. Events that contribute to HIV transcriptional latency include repressive chromatin structure, transcriptional interference, the inability of Tat to recruit positive transcription factor b, and poor processiv...

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Main Authors: Natarajan, Malini, Schiralli Lester, Gillian M., Lee, Chanhyo, Missra, Anamika, Wasserman, Gregory A., Steffen, Martin, Gilmour, David. S., Henderson, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Gene Regulation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764804/
https://ncbi.nlm.nih.gov/pubmed/23884411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.496489
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