Ganglioside GM1-mediated Transcytosis of Cholera Toxin Bypasses the Retrograde Pathway and Depends on the Structure of the Ceramide Domain

Cholera toxin causes diarrheal disease by binding ganglioside GM1 on the apical membrane of polarized intestinal epithelial cells and trafficking retrograde through sorting endosomes, the trans-Golgi network (TGN), and into the endoplasmic reticulum. A fraction of toxin also moves from endosomes acr...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Saslowsky, David E., te Welscher, Yvonne M., Chinnapen, Daniel J.-F., Wagner, Jessica S., Wan, Joy, Kern, Eli, Lencer, Wayne I.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2013
Ämnen:
Membrane Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764787/
https://ncbi.nlm.nih.gov/pubmed/23884419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.474957
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk