Lipid-sorting by ceramide structure from plasma membrane to ER for the cholera toxin receptor ganglioside GM1

The glycosphingolipid GM1 binds cholera toxin (CT) on host cells and carries it retrograde from the plasma membrane (PM) through endosomes, the trans-Golgi (TGN), and the endoplasmic reticulum (ER) to induce toxicity. To elucidate how a membrane lipid can specify trafficking in these pathways, we sy...

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Bibliografski detalji
Glavni autori: Chinnapen, Daniel J.-F., Hsieh, Wan-Ting, te Welscher, Yvonne M., Saslowsky, David E., Kaoutzani, Lydia, Brandsma, Eelke, D’Auria, Ludovic, Park, Hyejung, Wagner, Jessica S., Drake, Kimberly R., Kang, Minchul, Benjamin, Thomas, Ullman, M. David, Costello, Catherine E., Kenworthy, Anne K., Baumgart, Tobias, Massol, Ramiro H., Lencer, Wayne I.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443397/
https://ncbi.nlm.nih.gov/pubmed/22975326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.08.002
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