טוען...

Ganglioside GM1-mediated Transcytosis of Cholera Toxin Bypasses the Retrograde Pathway and Depends on the Structure of the Ceramide Domain

Cholera toxin causes diarrheal disease by binding ganglioside GM1 on the apical membrane of polarized intestinal epithelial cells and trafficking retrograde through sorting endosomes, the trans-Golgi network (TGN), and into the endoplasmic reticulum. A fraction of toxin also moves from endosomes acr...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Saslowsky, David E., te Welscher, Yvonne M., Chinnapen, Daniel J.-F., Wagner, Jessica S., Wan, Joy, Kern, Eli, Lencer, Wayne I.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764787/
https://ncbi.nlm.nih.gov/pubmed/23884419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.474957
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