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An auto-inhibited state in the structure of Thermotoga maritima NusG

NusG is a conserved regulatory protein interacting with RNA polymerase (RNAP) and other proteins to form multi-component complexes that modulate transcription. The crystal structure of Thermotoga maritima NusG (TmNusG) shows a three-domain architecture, comprising well conserved amino-terminal (NTD)...

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Autores principales: Drögemüller, Johanna, Stegmann, Christian M., Mandal, Angshuman, Steiner, Thomas, Burmann, Björn M., Gottesman, Max E., Wöhrl, Birgitta M., Rösch, Paul, Wahl, Markus C., Schweimer, Kristian
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764593/
https://ncbi.nlm.nih.gov/pubmed/23415559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.12.015
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