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Quality Score Based Identification and Correction of Pyrosequencing Errors

Massively-parallel DNA sequencing using the 454/pyrosequencing platform allows in-depth probing of diverse sequence populations, such as within an HIV-1 infected individual. Analysis of this sequence data, however, remains challenging due to the shorter read lengths relative to that obtained by Sang...

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Detalhes bibliográficos
Main Authors: Iyer, Shyamala, Bouzek, Heather, Deng, Wenjie, Larsen, Brendan, Casey, Eleanor, Mullins, James I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764156/
https://ncbi.nlm.nih.gov/pubmed/24039850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073015
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