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Bifunctional cinchona alkaloid-squaramide-catalyzed highly enantioselective aza-Michael addition of indolines to α,β-unsaturated ketones
An enantioselective aza-Michael addition of indolines to α,β-unsaturated ketones was achieved using a bifunctional cinchona alkaloid-derived chiral squaramide derivative. Various β-indolinyl ketone derivatives were obtained in good to excellent yields and with high enantioselectivity. DDQ or MnO(2)...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3763959/ https://ncbi.nlm.nih.gov/pubmed/24014895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2013.04.080 |
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