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Cinchona alkaloid catalyzed enantioselective amination of α,β-unsaturated ketones: an asymmetric approach to Δ(2)-pyrazolines
Δ(2)-Pyrazolines are of significant medicinal and synthetic interest due to their therapeutic properties and utility in the synthesis of 1,3-diamines, yet few asymmetric methods exist to prepare them. An unprecedented highly enantioselective organocatalytic synthesis of 2-pyrazolines was achieved th...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3692356/ https://ncbi.nlm.nih.gov/pubmed/23807876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adsc.201100447 |
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