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How Cinchona Alkaloid-Derived Primary Amines Control Asymmetric Electrophilic Fluorination of Cyclic Ketones

[Image: see text] The origin of selectivity in the α-fluorination of cyclic ketones catalyzed by cinchona alkaloid-derived primary amines is determined with density functional calculations. The chair preference of a seven-membered ring at the fluorine transfer transition state is key in determining...

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Bibliografiset tiedot
Päätekijät: Lam, Yu-hong, Houk, K. N.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2014
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105079/
https://ncbi.nlm.nih.gov/pubmed/24967514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja504714m
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