Role of Growth Arrest and DNA Damage–inducible α in Akt Phosphorylation and Ubiquitination after Mechanical Stress-induced Vascular Injury

Rationale: The stress-induced growth arrest and DNA damage–inducible α (GADD45a) gene is up-regulated by mechanical stress with GADD45a knockout (GADD45a(−/−)) mice demonstrating both increased susceptibility to ventilator-induced lung injury (VILI) and reduced levels of the cell survival and vascul...

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Main Authors: Mitra, Sumegha, Sammani, Saad, Wang, Ting, Boone, David L., Meyer, Nuala J., Dudek, Steven M., Moreno-Vinasco, Liliana, Garcia, Joe G. N., Jacobson, Jeffrey R.
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2011
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763933/
https://ncbi.nlm.nih.gov/pubmed/21816939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201103-0447OC
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