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A second generation MRI contrast agent for imaging zinc ions in vivo

A Zn(2+) specific GdDOTA derivative containing two bis-(3-pyrazolyl) units was prepared and characterized. Unlike a previously reported Zn(2+) binding agent, the new agent binds to human albumin both in the presence and absence of Zn(2+).

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Detalhes bibliográficos
Main Authors: De León-Rodríguez, Luis M., Lubag, Angelo J. M., López, Jorge A., Andreu-de-Riquer, Gabriel, Alvarado-Monzón, José C., Sherry, A. Dean
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763856/
https://ncbi.nlm.nih.gov/pubmed/24013159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C2MD00301E
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