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Genotoxicity-Related Chemistry of Human Metabolites of Benzo[ghi]perylene (B[ghi]P) Investigated using Electro-optical Arrays and DNA/Microsome Biocolloid Reactors with LC-MS/MS

There is limited and sometimes contradictory information about the genotoxicity of polycyclic aromatic hydrocarbon benzo[ghi]perylene (B[ghi]P). Using recently developed metabolic toxicity screening arrays and a biocolloid reactor-LC-MS/MS approach, both featuring films of DNA and human metabolic en...

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Bibliographic Details
Main Authors: Pan, Shenmin, Li, Dandan, Zhao, Linlin, Schenkman, John B., Rusling, James F.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763812/
https://ncbi.nlm.nih.gov/pubmed/23879290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx400147c
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