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High Throughput Metabolic Toxicity Screening Using Magnetic Biocolloid Reactors and LC-MS/MS

An inexpensive, high-throughput genotoxicity screening method was developed by using magnetic particles coated with cytosol/microsome/DNA films as biocolloid reactors in 96-well plate format coupled with liquid chromatography-mass spectrometry. Incorporation of both microsomal and cytosolic enzymes...

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Detalhes bibliográficos
Main Authors: Zhao, Linlin, Schenkman, John B., Rusling, James F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005372/
https://ncbi.nlm.nih.gov/pubmed/21090635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac102317a
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