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Evaluation of Electrochemiluminescent Metabolic Toxicity Screening Arrays Using a Multiple Compound Set

Arrays for screening metabolite-generated toxicity utilizing spots containing DNA, enzyme and electroluminescent (ECL) polymer ([Ru(bpy)(2)PVP(10)](2+)) were extended to include a fully representative set of metabolic enzymes from human and rat liver microsomes, human and rat liver cytosol, and mous...

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Autors principals: Pan, Shenmin, Zhao, Linlin, Schenkman, John B., Rusling, James F.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069143/
https://ncbi.nlm.nih.gov/pubmed/21395325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac200050n
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