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An evolutionary perspective on the broad antiviral specificity of MxA

Germ line encoded antiviral defenses in vertebrate cells tend to be either broadly acting factors that exploit general features of viral replication or effectors with strong pathogen preference by virtue of specific recognition of viral proteins. The Mx GTPases, however, are atypical since they have...

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Autores principales: Mitchell, Patrick S., Emerman, Michael, Malik, Harmit S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763691/
https://ncbi.nlm.nih.gov/pubmed/23725670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mib.2013.04.005
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