Zinc-finger-nucleases mediate specific and efficient excision of HIV-1 proviral DNA from infected and latently infected human T cells

HIV-infected individuals currently cannot be completely cured because existing antiviral therapy regimens do not address HIV provirus DNA, flanked by long terminal repeats (LTRs), already integrated into host genome. Here, we present a possible alternative therapeutic approach to specifically and di...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Qu, Xiying, Wang, Pengfei, Ding, Donglin, Li, Lin, Wang, Haibo, Ma, Li, Zhou, Xin, Liu, Shaohui, Lin, Shiguan, Wang, Xiaohui, Zhang, Gongmin, Liu, Sijie, Liu, Lin, Wang, Jianhua, Zhang, Feng, Lu, Daru, Zhu, Huanzhang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763554/
https://ncbi.nlm.nih.gov/pubmed/23804764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt571
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados