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Simultaneous Screening and Validation of Effective Zinc Finger Nucleases in Yeast

Zinc finger nucleases (ZFNs) have been successfully used for genome modification in various cell types and species. However, construction of an effective ZFN remained challenging. Previous studies all focused on obtaining specific zinc finger proteins (ZFPs) first via bacterial 2-hybrid approach, an...

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Detalhes bibliográficos
Main Authors: Wang, Ling, Lin, Juan, Zhang, Tingting, Xu, Kun, Ren, Chonghua, Zhang, Zhiying
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669427/
https://ncbi.nlm.nih.gov/pubmed/23741369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064687
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