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Structural insight into negative DNA supercoiling by DNA gyrase, a bacterial type 2A DNA topoisomerase
Type 2A DNA topoisomerases (Topo2A) remodel DNA topology during replication, transcription and chromosome segregation. These multisubunit enzymes catalyze the transport of a double-stranded DNA through a transient break formed in another duplex. The bacterial DNA gyrase, a target for broad-spectrum...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3763546/ https://ncbi.nlm.nih.gov/pubmed/23804759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt560 |
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