Nuclear CaMKII enhances histone H3 phosphorylation and remodels chromatin during cardiac hypertrophy

Calcium/calmodulin-dependent protein kinase II (CaMKII) plays a central role in pathological cardiac hypertrophy, but the mechanisms by which it modulates gene activity in the nucleus to mediate hypertrophic signaling remain unclear. Here, we report that nuclear CaMKII activates cardiac transcriptio...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Awad, Salma, Kunhi, Muhammad, Little, Gillian H., Bai, Yan, An, Woojin, Bers, Donald, Kedes, Larry, Poizat, Coralie
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Gene Regulation, Chromatin and Epigenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763528/
https://ncbi.nlm.nih.gov/pubmed/23804765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt500
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker