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A Proteasome Assembly Defect in rpn3 Mutants Is Associated with Rpn11 Instability and Increased Sensitivity to Stress
Rpn11 is a proteasome-associated deubiquitinating enzyme that is essential for viability. Recent genetic studies showed that Rpn11 is functionally linked to Rpn10, a major multiubiquitin chain binding receptor in the proteasome. Mutations in Rpn11 and Rpn10 can reduce the level and/or stability of p...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3763486/ https://ncbi.nlm.nih.gov/pubmed/21619884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.05.005 |
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