A Proteasome Assembly Defect in rpn3 Mutants Is Associated with Rpn11 Instability and Increased Sensitivity to Stress

Rpn11 is a proteasome-associated deubiquitinating enzyme that is essential for viability. Recent genetic studies showed that Rpn11 is functionally linked to Rpn10, a major multiubiquitin chain binding receptor in the proteasome. Mutations in Rpn11 and Rpn10 can reduce the level and/or stability of p...

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Hlavní autoři: Joshi, Kishore Kumar, Chen, Li, Torres, Nidza, Tournier, Vincent, Madura, Kiran
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763486/
https://ncbi.nlm.nih.gov/pubmed/21619884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.05.005
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