A ginseng metabolite, compound K, induces autophagy and apoptosis via generation of reactive oxygen species and activation of JNK in human colon cancer cells

Compound K (20-O-(β-D-glucopyranosyl)-20(S)-protopanaxadiol) is an active metabolite of ginsenosides and induces apoptosis in various types of cancer cells. This study investigated the role of autophagy in compound K-induced cell death of human HCT-116 colon cancer cells. Compound K activated an aut...

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Main Authors: Kim, A D, Kang, K A, Kim, H S, Kim, D H, Choi, Y H, Lee, S J, Hyun, J W
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2013
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763435/
https://ncbi.nlm.nih.gov/pubmed/23907464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.273
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