Compound K, a Metabolite of Ginseng Saponin, Induces Mitochondria-Dependent and Caspase-Dependent Apoptosis via the Generation of Reactive Oxygen Species in Human Colon Cancer Cells

The objective of this study was to elucidate the cytotoxic mechanism of Compound K, with respect to the involvement of reactive oxygen species (ROS) and the mitochondrial involved apoptosis, in HT-29 human colon cancer cells. Compound K exhibited a concentration of 50% growth inhibition (IC(50)) at...

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Bibliografiske detaljer
Main Authors: Lee, In Kyung, Kang, Kyoung Ah, Lim, Chae Moon, Kim, Ki Cheon, Kim, Hee Sun, Kim, Dong Hyun, Kim, Bum Joon, Chang, Weon Young, Choi, Jae Hyuck, Hyun, Jin Won
Format: Artigo
Sprog:Inglês
Udgivet: Molecular Diversity Preservation International (MDPI) 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100836/
https://ncbi.nlm.nih.gov/pubmed/21614182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms11124916
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