Compound K, a Metabolite of Ginseng Saponin, Induces Mitochondria-Dependent and Caspase-Dependent Apoptosis via the Generation of Reactive Oxygen Species in Human Colon Cancer Cells

The objective of this study was to elucidate the cytotoxic mechanism of Compound K, with respect to the involvement of reactive oxygen species (ROS) and the mitochondrial involved apoptosis, in HT-29 human colon cancer cells. Compound K exhibited a concentration of 50% growth inhibition (IC(50)) at...

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Detalhes bibliográficos
Main Authors: Lee, In Kyung, Kang, Kyoung Ah, Lim, Chae Moon, Kim, Ki Cheon, Kim, Hee Sun, Kim, Dong Hyun, Kim, Bum Joon, Chang, Weon Young, Choi, Jae Hyuck, Hyun, Jin Won
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100836/
https://ncbi.nlm.nih.gov/pubmed/21614182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms11124916
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