Compound K, a metabolite of ginseng saponin, induces apoptosis via caspase-8-dependent pathway in HL-60 human leukemia cells

BACKGROUND: Compound K [20-O-β-(D-glucopyranosyl)-20(S)-protopanaxadiol], a metabolite of the protopanaxadiol-type saponins of Panax ginseng C.A. Meyer, has been reported to possess anti-tumor properties to inhibit angiogenesis and to induce tumor apoptosis. In the present study, we investigated the...

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Main Authors: Cho, Sung-Hee, Chung, Kyung-Sook, Choi, Jung-Hye, Kim, Dong-Hyun, Lee, Kyung-Tae
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806409/
https://ncbi.nlm.nih.gov/pubmed/20017956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-449
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