May the Evaluation of Nitrosative Stress Through Selective Increase of 3-Nitrotyrosine Proteins Other Than Nitroalbumin and Dominant Tyrosine-125/136 Nitrosylation of Serum α-Synuclein Serve for Diagnosis of Sporadic Parkinson's Disease?

Nitrosative stress, where nitrosylation of tyrosine (Tyr) leading to 3-nitrotyrosine proteins or free 3-nitrotyrosine is the most prominent change, has been proposed as a pathogenic mechanism in Parkinson's disease (PD). Levels of 3-nitrotyrosine proteins in serum and cerebrospinal fluid (CSF)...

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Autors principals: Fernández, Emilio, García-Moreno, José-Manuel, Martín de Pablos, Angel, Chacón, José
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2013
Matèries:
News & Views
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763231/
https://ncbi.nlm.nih.gov/pubmed/23418747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5250
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