Sphingosine 1-Phosphate Counteracts the Effects of Interleukin-1β in Human Chondrocytes

OBJECTIVE: The lipid mediator sphingosine 1-phosphate (S1P) is found in the synovial fluid of osteoarthritis (OA) patients. S1P protects bovine cartilage by counteracting the effects of interleukin-1β (IL-1β). This study was undertaken to examine the interaction of S1P and IL-1β in human OA chondroc...

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Main Authors: Stradner, Martin H, Gruber, Gerald, Angerer, Hannes, Huber, Verena, Setznagl, Daniela, Kremser, Marie-Luise, Moazedi-Fürst, Florentine C, Windhager, Reinhard, Graninger, Winfried B
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Chondrocyte Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763206/
https://ncbi.nlm.nih.gov/pubmed/23666803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.37989
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