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A novel role of sphingosine 1-phosphate receptor S1pr1 in mouse thrombopoiesis

Millions of platelets are produced each hour by bone marrow (BM) megakaryocytes (MKs). MKs extend transendothelial proplatelet (PP) extensions into BM sinusoids and shed new platelets into the blood. The mechanisms that control platelet generation remain incompletely understood. Using conditional mu...

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Detalhes bibliográficos
Main Authors: Zhang, Lin, Orban, Martin, Lorenz, Michael, Barocke, Verena, Braun, Daniel, Urtz, Nicole, Schulz, Christian, von Brühl, Marie-Luise, Tirniceriu, Anca, Gaertner, Florian, Proia, Richard L., Graf, Thomas, Bolz, Steffen-Sebastian, Montanez, Eloi, Prinz, Marco, Müller, Alexandra, von Baumgarten, Louisa, Billich, Andreas, Sixt, Michael, Fässler, Reinhard, von Andrian, Ulrich H., Junt, Tobias, Massberg, Steffen
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501353/
https://ncbi.nlm.nih.gov/pubmed/23148237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20121090
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