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Pseudophosphorylated αB-Crystallin Is a Nuclear Chaperone Imported into the Nucleus with Help of the SMN Complex

The human small heat shock protein αB-crystallin (HspB5) is a molecular chaperone which is mainly localized in the cytoplasm. A small fraction can also be found in nuclear speckles, of which the localization is mediated by successional phosphorylation at Ser-59 and Ser-45. αB-crystallin does not con...

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Hlavní autoři: den Engelsman, John, van de Schootbrugge, Chantal, Yong, Jeongsik, Pruijn, Ger J. M., Boelens, Wilbert C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762725/
https://ncbi.nlm.nih.gov/pubmed/24023879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073489
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