Attenuated RhoA/Rho-kinase Signaling in the Penis of Transgenic Sickle Cell Mice

OBJECTIVES: RhoA and its main downstream effector, Rho-kinase (ROCK) are important in maintaining the penis in the flaccid state. The pathophysiology of Sickle cell disease-associated priapism is not well defined. We hypothesize that RhoA/ROCK vasoconstrictive pathways may be involved in the develop...

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Main Authors: Bivalacqua, Trinity J., Ross, Ashley E., Strong, Travis D., Gebska, Milena A., Musicki, Biljana, Champion, Hunter C., Burnett, Arthur L.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762569/
https://ncbi.nlm.nih.gov/pubmed/20538321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.urology.2010.02.050
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