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Attenuated RhoA/Rho-kinase Signaling in the Penis of Transgenic Sickle Cell Mice
OBJECTIVES: RhoA and its main downstream effector, Rho-kinase (ROCK) are important in maintaining the penis in the flaccid state. The pathophysiology of Sickle cell disease-associated priapism is not well defined. We hypothesize that RhoA/ROCK vasoconstrictive pathways may be involved in the develop...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3762569/ https://ncbi.nlm.nih.gov/pubmed/20538321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.urology.2010.02.050 |
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