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Cytoplasmic dynein crosslinks and slides anti-parallel microtubules using its two motor domains
Cytoplasmic dynein is the predominant minus-end-directed microtubule (MT) motor in most eukaryotic cells. In addition to transporting vesicular cargos, dynein helps to organize MTs within MT networks such as mitotic spindles. How dynein performs such non-canonical functions is unknown. Here we demon...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
eLife Sciences Publications, Ltd
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3762337/ https://ncbi.nlm.nih.gov/pubmed/24015359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00943 |
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