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Sildenafil therapy in thalassemia patients with Doppler-defined risk of pulmonary hypertension

Pulmonary hypertension is a common but often overlooked complication associated with thalassemia syndromes. There are limited data on the safety and efficacy of selective pulmonary vasodilators in this at-risk population. We, therefore, designed a 12-week, open-label, phase 1/2, pilot-scale, proof-o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Morris, Claudia R., Kim, Hae-Young, Wood, John, Porter, John B., Klings, Elizabeth S., Trachtenberg, Felicia L., Sweeters, Nancy, Olivieri, Nancy F., Kwiatkowski, Janet L., Virzi, Lisa, Singer, Sylvia T., Taher, Ali, Neufeld, Ellis J., Thompson, Alexis A., Sachdev, Vandana, Larkin, Sandra, Suh, Jung H., Kuypers, Frans A., Vichinsky, Elliott P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ferrata Storti Foundation 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762091/
https://ncbi.nlm.nih.gov/pubmed/23585527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.082065
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