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Sildenafil therapy in thalassemia patients with Doppler-defined risk of pulmonary hypertension

Pulmonary hypertension is a common but often overlooked complication associated with thalassemia syndromes. There are limited data on the safety and efficacy of selective pulmonary vasodilators in this at-risk population. We, therefore, designed a 12-week, open-label, phase 1/2, pilot-scale, proof-o...

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Bibliografski detalji
Glavni autori: Morris, Claudia R., Kim, Hae-Young, Wood, John, Porter, John B., Klings, Elizabeth S., Trachtenberg, Felicia L., Sweeters, Nancy, Olivieri, Nancy F., Kwiatkowski, Janet L., Virzi, Lisa, Singer, Sylvia T., Taher, Ali, Neufeld, Ellis J., Thompson, Alexis A., Sachdev, Vandana, Larkin, Sandra, Suh, Jung H., Kuypers, Frans A., Vichinsky, Elliott P.
Format: Artigo
Jezik:Inglês
Izdano: Ferrata Storti Foundation 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762091/
https://ncbi.nlm.nih.gov/pubmed/23585527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.082065
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