Sildenafil therapy in thalassemia patients with Doppler-defined risk of pulmonary hypertension

Pulmonary hypertension is a common but often overlooked complication associated with thalassemia syndromes. There are limited data on the safety and efficacy of selective pulmonary vasodilators in this at-risk population. We, therefore, designed a 12-week, open-label, phase 1/2, pilot-scale, proof-o...

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Autori principali: Morris, Claudia R., Kim, Hae-Young, Wood, John, Porter, John B., Klings, Elizabeth S., Trachtenberg, Felicia L., Sweeters, Nancy, Olivieri, Nancy F., Kwiatkowski, Janet L., Virzi, Lisa, Singer, Sylvia T., Taher, Ali, Neufeld, Ellis J., Thompson, Alexis A., Sachdev, Vandana, Larkin, Sandra, Suh, Jung H., Kuypers, Frans A., Vichinsky, Elliott P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762091/
https://ncbi.nlm.nih.gov/pubmed/23585527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.082065
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