Sildenafil therapy in thalassemia patients with Doppler-defined risk of pulmonary hypertension

Pulmonary hypertension is a common but often overlooked complication associated with thalassemia syndromes. There are limited data on the safety and efficacy of selective pulmonary vasodilators in this at-risk population. We, therefore, designed a 12-week, open-label, phase 1/2, pilot-scale, proof-o...

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Autors principals: Morris, Claudia R., Kim, Hae-Young, Wood, John, Porter, John B., Klings, Elizabeth S., Trachtenberg, Felicia L., Sweeters, Nancy, Olivieri, Nancy F., Kwiatkowski, Janet L., Virzi, Lisa, Singer, Sylvia T., Taher, Ali, Neufeld, Ellis J., Thompson, Alexis A., Sachdev, Vandana, Larkin, Sandra, Suh, Jung H., Kuypers, Frans A., Vichinsky, Elliott P.
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2013
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762091/
https://ncbi.nlm.nih.gov/pubmed/23585527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.082065
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