Sildenafil therapy in thalassemia patients with Doppler-defined risk of pulmonary hypertension

Pulmonary hypertension is a common but often overlooked complication associated with thalassemia syndromes. There are limited data on the safety and efficacy of selective pulmonary vasodilators in this at-risk population. We, therefore, designed a 12-week, open-label, phase 1/2, pilot-scale, proof-o...

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Auteurs principaux: Morris, Claudia R., Kim, Hae-Young, Wood, John, Porter, John B., Klings, Elizabeth S., Trachtenberg, Felicia L., Sweeters, Nancy, Olivieri, Nancy F., Kwiatkowski, Janet L., Virzi, Lisa, Singer, Sylvia T., Taher, Ali, Neufeld, Ellis J., Thompson, Alexis A., Sachdev, Vandana, Larkin, Sandra, Suh, Jung H., Kuypers, Frans A., Vichinsky, Elliott P.
Format: Artigo
Langue:Inglês
Publié: Ferrata Storti Foundation 2013
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762091/
https://ncbi.nlm.nih.gov/pubmed/23585527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.082065
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