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Clinical implications of microsatellite instability in sporadic colon cancers
PURPOSE OF REVIEW: To review data demonstrating the prognostic and predictive impact of microsatellite instability (MSI) in human colon carcinomas. RECENT FINDINGS: MSI is a molecular marker of defective DNA mismatch repair that is detected in approximately 15% of sporadic colon cancers. Most, but n...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3761884/ https://ncbi.nlm.nih.gov/pubmed/19444104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCO.0b013e32832c94bd |
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