The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis

NLRP12 is a member of the intracellular Nod-like receptor (NLR) family that has been suggested to down-regulate the production of inflammatory cytokines, but its physiological role in regulating inflammation has not been characterized. We generated mice deficient in Nlrp12 and studied its role in in...

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Главные авторы: Zaki, Md. Hasan, Vogel, Peter, Subbarao Malireddi, R. K., Body-Malapel, Mathilde, Anand, Paras K., Bertin, John, Green, Douglas R., Lamkanfi, Mohamed, Kanneganti, Thirumala-Devi
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761879/
https://ncbi.nlm.nih.gov/pubmed/22094258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2011.10.022
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