NLRP6 Negatively Regulates Innate Immunity and Host Defense Against Bacterial Pathogens

Members of the intracellular nucleotide-binding and oligomerization domain (NOD)-like receptor (NLR) family contribute to immune responses through activation of NF-κB, type I interferon and inflammasome signaling(1). Mice lacking the NLR family member NLRP6 were recently shown to be susceptible to c...

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Библиографические подробности
Главные авторы: Anand, Paras K., Malireddi, R. K. Subbarao, Lukens, John R., Vogel, Peter, Bertin, John, Lamkanfi, Mohamed, Kanneganti, Thirumala-Devi
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422416/
https://ncbi.nlm.nih.gov/pubmed/22763455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11250
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