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IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation
Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. Chronic inflammation is recognized as a predisposing factor for the development of colon cancer, but the molecular mechanisms linking inflammation and tumorigenesis remained elusive. Recent studies revealed a crucial role...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3104023/ https://ncbi.nlm.nih.gov/pubmed/20855874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002046 |
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