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Caspase-dependent regulation of the ubiquitin–proteasome system through direct substrate targeting
Drosophila inhibitor of apoptosis (IAP) 1 (DIAP1) is an E3 ubiquitin ligase that regulates apoptosis in flies, in large part through direct inhibition and/or ubiquitinylation of caspases. IAP antagonists, such as Reaper, Hid, and Grim, are thought to induce cell death by displacing active caspases f...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3761634/ https://ncbi.nlm.nih.gov/pubmed/23940367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306179110 |
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