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Ubiquitin degradation with its substrate, or as a monomer in a ubiquitination-independent mode, provides clues to proteasome regulation

The mechanisms that regulate the ubiquitin (Ub)-proteasome system's own components, although critically important, are largely unknown. Ub, a principal component of the system, must be maintained at adequate levels to support cellular homeostasis under basal and stressed conditions. It was sugg...

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Detalhes bibliográficos
Main Authors: Shabek, Nitzan, Herman-Bachinsky, Yifat, Ciechanover, Aaron
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715473/
https://ncbi.nlm.nih.gov/pubmed/19581590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905746106
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