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Human NAIP and mouse NAIP1 recognize bacterial type III secretion needle protein for inflammasome activation

Inflammasome mediated by central nucleotide-binding and oligomerization domain (NOD)-like receptor (NLR) protein is critical for defense against bacterial infection. Here we show that type III secretion system (T3SS) needle proteins from several bacterial pathogens, including Salmonella typhimurium,...

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Detalhes bibliográficos
Main Authors: Yang, Jieling, Zhao, Yue, Shi, Jianjin, Shao, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761597/
https://ncbi.nlm.nih.gov/pubmed/23940371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306376110
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