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Mouse NAIP1 detects the type III secretion system needle protein
The NAIP/NLRC4 inflammasomes activate caspase-1 in response to bacterial type III secretion systems (T3SS). Inadvertent injection of the T3SS rod protein and flagellin into the cytosol are detected through murine NAIP2 and NAIP5/6, respectively. Here, we identify the agonist for the orphan murine NA...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3819181/ https://ncbi.nlm.nih.gov/pubmed/24043898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301549 |
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