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Thromboxane-induced renal vasoconstriction is mediated by the ADP-ribosyl cyclase CD38 and superoxide anion

The present renal hemodynamic study tested the hypothesis that CD38 and superoxide anion (O(2)(·−)) participate in the vasoconstriction produced by activation of thromboxane prostanoid (TP) receptors in the mouse kidney. CD38 is the major mammalian ADP-ribosyl cyclase contributing to vasomotor tone...

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Autori principali: Moss, Nicholas G., Vogel, Paul A., Kopple, Tayler E., Arendshorst, William J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761291/
https://ncbi.nlm.nih.gov/pubmed/23884143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00048.2013
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