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ADP-ribosyl cyclase and ryanodine receptors mediate endothelin ET(A) and ET(B) receptor-induced renal vasoconstriction in vivo

ADP-ribosyl cyclase (ADPR cyclase) and ryanodine receptors (RyR) participate in calcium transduction in isolated afferent arterioles. We hypothesized that this signaling pathway is activated by ET(A) and ET(B) receptors in the renal vasculature to mediate vasoconstriction in vivo. To test this, we m...

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Bibliografiske detaljer
Main Authors: Thai, Tiffany L., Arendshorst, William J.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519186/
https://ncbi.nlm.nih.gov/pubmed/18524860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00512.2007
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