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Renal vasoconstriction by vasopressin V(1a) receptors is modulated by nitric oxide, prostanoids, and superoxide but not the ADP ribosyl cyclase CD38

Renal blood flow (RBF) responses to arginine vasopressin (AVP) were tested in anesthetized wild-type (WT) and CD38(−/−) mice that lack the major calcium-mobilizing second messenger cyclic ADP ribose. AVP (3–25 ng) injected intravenously produced dose-dependent decreases in RBF, reaching a maximum of...

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Autors principals: Moss, Nicholas G., Kopple, Tayler E., Arendshorst, William J.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024735/
https://ncbi.nlm.nih.gov/pubmed/24623148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00664.2013
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