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Renal vasoconstriction by vasopressin V(1a) receptors is modulated by nitric oxide, prostanoids, and superoxide but not the ADP ribosyl cyclase CD38
Renal blood flow (RBF) responses to arginine vasopressin (AVP) were tested in anesthetized wild-type (WT) and CD38(−/−) mice that lack the major calcium-mobilizing second messenger cyclic ADP ribose. AVP (3–25 ng) injected intravenously produced dose-dependent decreases in RBF, reaching a maximum of...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4024735/ https://ncbi.nlm.nih.gov/pubmed/24623148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00664.2013 |
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