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Pertussis Toxin B-Pentamer Mediates Intercellular Transfer of Membrane Proteins and Lipids

Pertussis toxin (PTx) is the major virulence factor of Bordetella pertussis. The enzymatic or active (A) subunit inactivates host G protein coupled receptor (GPCR) signaling pathways. The non-enzymatic binding (B) subunit also mediates biological effects due to lectin-like binding characteristics, i...

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Detalhes bibliográficos
Main Authors: Millen, Scott H., Schneider, Olivia D., Miller, William E., Monaco, John J., Weiss, Alison A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760862/
https://ncbi.nlm.nih.gov/pubmed/24019885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072885
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