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Pertussis Toxin Signals through the TCR to Initiate Cross-Desensitization of the Chemokine Receptor CXCR4

Pertussis toxin (PTx) has been shown to exert a variety of effects on immune cells independent of its ability to ADP-ribosylate G proteins. Of these effects, the binding subunit of PTx (PTxB) has been shown to block signaling via the chemokine receptor CCR5, but the mechanism involved in this proces...

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Detalhes bibliográficos
Main Authors: Schneider, Olivia D., Weiss, Alison A., Miller, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766007/
https://ncbi.nlm.nih.gov/pubmed/19380820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803114
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